Telomerase Stimulation Extends Lifespan in Mice

Stimulation of telomerase safely extends lifespan in mice, a new study shows.

In a landmark study demonstrating “proof of principle” of the feasibility and safety of “slowing or turning back the clock,” Spanish researchers gave aged mice a single treatment to stimulate genetic expression of telomerase that extended health and lifespan by up to 24 percent.

These new results serve as yet more validation of research performed by Isagenix Founder John Anderson in partnership with molecular biologist Bill Andrews, Ph.D., on inducing the expression of telomerase in humans with natural compounds for healthier aging and greater longevity. This research is what led to the creation of Isagenix product, Product B.

Although previous research has long suggested telomerase expression would maximize the potential for cells to replicate, Maria Blasco, Ph.D., and fellow researchers from the Spanish National Cancer Centre (CNIO) showed unequivocally that increasing this enzyme in aging mice improves health and extends lifespan safely without any increase in rates of cancer. Continue reading

Science Behind “Living Forever”

On the TODAY Show, Dr. Andrews and his father, Ralph, exemplify what it means to defy aging through exercise and supplementation.

“Could people soon be living forever?” A story by Linda Carroll posted on MSN.com, based on TODAY Show reporting by Michelle Kosinski, brings more attention to this captivating question and to the scientists researching all aspects approaching it, including telomere biologist Bill Andrews, Ph.D.

In the story, Dr. Andrews is credited for his work in the development of a supplement that is said to help keep “telomeres from shortening with age.” The supplement, created by Isagenix Founder John Anderson in collaboration with Dr. Andrews, is Isagenix Product B™.

Carrol’s report describes telomeres, the complex non-coding DNA structures at the tips of chromosomes that act as protective caps, and how as they “become shorter, we deteriorate.”

Dr. Andrews is quoted as saying, “The literature is, I would say, 95 percent certain or better that if we can find ways to lengthen the telomeres, we are going to reverse aging.” Continue reading

Exercise and Physical Ability are Associated with Longer Telomeres

Staying physically active leads to increased telomere length, according to study

It’s about that time to get up and do your workout. Despite your everyday stress, you just know you should do it. Think of the benefits to your cardiovascular system, the endorphin-stimulated “rush” you feel during and after the workout, and finally, the slimming effect on your waistline. Now, you can add an anti-aging effect on telomeres.

As anyone taking Isagenix Product B knows, telomere support is a key component towards slowing down the age clock. Telomeres, those complex DNA structures at the tips of our chromosomes, shorten with age normally; however, this shortening and aging is accelerated by many lifestyle factors: obesity, toxins, oxidative stress, psychological stress, and poor nutrition. This is why Isagenix has developed a variety of products, our Pillars of Health (Cleanse for Life, IsaLean Shake, Ionix Supreme, Ageless Essentials Daily Pak with Product B), to target each of these age-accelerating factors.

To that list of age-defying pillars, don’t forget to add physical activity. In a new paper published in the journal Mechanisms of Aging and Development, researchers from Denmark have provided evidence that an increase in physical ability was positively associated with longer telomeres. In fact, they even calculated how many years increased physical ability could contribute to longer lifespans. Continue reading

The Isagenix Lifestyle for Ultimate Telomere Health

New Ageless Essentials with Product B is advanced support for telomere health.

New Ageless Essentials with Product B is advanced support for telomere health.

The wait is over.

Nearly a year ago, we reported on the teaming up of Isagenix Founder and Master Formulator John Anderson and molecular biologist Bill Andrews, Ph.D. The two had just announced a strategic partnership wherein they would begin seeking out natural, safe compounds to create a revolutionary product that could help “turn back the clock” on aging.

The focus of their research would be telomerase, the enzyme that maintains telomeres, or the protective caps of chromosomes that shorten with age. Telomere length was already starting to become an exciting new biomarker of aging (1-4).

Over the next few months, Anderson and Dr. Andrews worked to verify the activity of a number of natural compounds and their ability to assist in the maintenance of telomere health. Then, within a year’s time, Anderson and Dr. Andrews had fantastic news: ”hits,” or discovery of natural compounds with potential of supporting telomere health; and a new product, Product B™ Antioxidants plus Telomere Support, which has garnered national media attention! Continue reading

Isagenix for Life: Shake Days and Cleanse Days

The Isagenix system combining Shake Days and Cleanse Days is a way to optimize health based on scientific studies.

The Isagenix system combining Shake Days and Cleanse Days is a way to optimize health based on scientific studies.

Isagenix products work, almost magically. This is a sentiment felt by thousands of satisfied customers who have found their products of choice for achieving weight loss, improved health, and feeling better using our signature Pillars of Health—Cleanse for Life, IsaLean Shake, Ionix Supreme, and Ageless Essentials Daily Pack combined with Product B. These products are used within a nutritionally sound program involving Shake Days and Cleanse Days and represent a convenient pathway toward:

  • Reducing body weight, body fat, and waist circumference
  • Improving insulin sensitivity and other metabolic markers
  • Reducing oxidative stress
  • Improving heart health by reducing cardiovascular risk factors
  • Promoting a longer life

Why do the products work so enchantingly well? How do they amaze people with weight loss, muscle building, and more energy? You could say The World Leader in Nutritional Cleansing, Replenishing, and Youthful Aging has a few tricks up its sleeves backed by the science of cleansing, minimized calories, and maximized nutrition.

Most low-calorie diets are strictly catabolic (causing tissue breakdown): fat and muscle break down, hunger is continuous, and feelings of fatigue are normal. Furthermore, these types of diets provide less than optimal nutrition to power the body or quality protein necessary to prevent long-term muscle loss. Micronutrient intake falters and cells begin to function less efficiently. Similarly, water (or even juice) fasting is short-term starvation, is catabolic, and puts the body into “slower metabolism” to conserve energy. In addition there are little if any nutrients provided by fasting, including the ones necessary for detoxification and guarding against toxins and oxidative stress.

In contrast, Cleanse Days provide a “jump start” for people so they can take control of their health and see wonderful results. Cleanse Days stimulate reduction of fat deposits that release stored toxins. The smaller the fat cells become, the less pro-inflammatory cytokines (signaling molecules) they produce—further reducing ill effects on the body. Cleanse for Life facilitates a healthier body by encouraging detoxification of these toxins whether they be endogenous (produced by the body) or exogenous (from our diets or environment). Cleanse Days provide some fuel and nutrients, thus allowing the digestion processes to rest and promoting detoxification in the liver and kidneys.  Continue reading