PrintDebunking Myths About Cyanocobalamin (B12)


Statements on the Internet claiming poor quality or toxicity from B12 in form of cyanocobalamin are enough to raise a few eyebrows. Good thing these claims are false!

The alarming argument is found on multiple Web pages that are usually linked with the sale of other versions of the vitamin, methylcobalamin or hydroxocobalamin. These sources claim higher-quality of their own supplements while discussing misleading information about B12 safety including that cyanocobalamin is a “junk” version of the vitamin that leaves toxic residues in the body. 

However, cyanocobalamin is not only the most stable version of the vitamin, which helps to ensure efficacy, but the evidence of safety is also very strong. According to a review in the Journal of American Medical Association and statements from the Council for Responsible Nutrition, even if taken in large amounts, any contribution of residues (cyanide) are regarded as “toxicologically insignificant”. In any form, there is no evidence of any adverse health effects from B12 even when taken in amounts well over the recommended dietary allowance.

There should be no concerns over the quality, safety or efficacy of B12 in the form of cyanocobalamin.

Vitamin B12 is one of many B vitamins important for supporting normal cell metabolism and energy production. The vitamin is found exclusively in animal foods such as meat and eggs. A deficiency of the vitamin can often occur in older people, those who suffer from impaired digestion including pernicious anemia, and vegetarians.